• Lana Lekić Faculty of Health Studies, University of Sarajevo,Sarajevo, Bosnia and Herzegovina
  • Bojan Pavlović MPT, Faculty of Sport and Physical Education Sarajevo, University of East Sarajevo,Sarajevo, Bosnia and Herzegovina



vitamin D, psoriasis, participants, scalp, joints, lumbal region, hands


Psoriasis represents a disorder of skin hypoproliferation, where vitamin D is frequently utilized in its treatment. Ultraviolet (UV) radiation stimulates the synthesis of vitamin D3 (cholecalciferol) in the epidermis. This compound undergoes further conversion into active metabolites, specifically 25-hydroxycholecalciferol and 1,25-hydroxycholecalciferol, which play crucial roles in skin health. However, in conditions like psoriasis, disruptions in skin functioning impede the cutaneous production of vitamin D, initiating a detrimental cycle. This disruption leads to a gradual reduction in vitamin D levels throughout the body, consequently destabilizing skin homeostasis. Topical application of vitamin D enables a substantial reduction in psoriasis on target areas of the body such as the scalp, joints, hands and lumbar region. The research records reductions of 100%, 80%, and 50% in the mentioned regions.


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How to Cite

Lekić, L., & Pavlović, B. (2024). TRANSDERMAL APPLICATION OF VITAMIN D AND ITS EFFECTS ON PSORIASIS. MEDIS – International Journal of Medical Sciences and Research, 3(1), 7–11.